Kyoto Univ. Eyes Clinical Study on iPS Cell-Derived Platelets

Society Lifestyle

Kyoto, Aug. 20 (Jiji Press)--A team of Kyoto University said Monday it has applied for approval by the health ministry of a plan to infuse platelets made from induced pluripotent stem cells into a sufferer of a serious blood disease.

The team, led by Prof. Koji Eto, filed the application last month after obtaining permission for the iPS cell-based clinical study from the university's screening committee in May, it said at a press conference in Kyoto.

A panel of the ministry is scheduled to discuss the plan on Aug. 29.

In the proposed project, a sufferer of aplastic anemia, which occurs when bone marrow stops producing blood cells including platelets, will receive transfusions of a large quantity of platelets derived from iPS cells on three occasions and be monitored for one year to check the safety of the method.

The researchers plan not to use iPS cells, which can develop into almost all kinds of tissue, made from donor cells and stocked at the university but to produce them from the patient's own blood cells to prevent a transfusion reaction.

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