In World's 1st, iPS-Based Cells Transplanted to Treat Parkinson's

Society Lifestyle Science Technology

Kyoto, Nov. 9 (Jiji Press)--Kyoto University said Friday that it has carried out the world's first transplant of nerve cells created from induced pluripotent stem, or iPS, cells, into the brain of a Parkinson's disease patient in a clinical trial.

The university plans to conduct transplant to a second patient after examining the safety of the treatment, including whether the nerve cells will develop into tumors.

According to the university, the first transplant surgery was performed on a man in his 50s. His ability to talk and walk has not changed since the operation.

Parkinson's disease causes sufferers to develop symptoms such as muscle stiffness and shaking body parts, due to a fall in the number of nerve cells that create dopamine, a substance to transmit signals in the brain. The number of sufferers in Japan is estimated at 160,000.

A team led by Kyoto University Prof. Jun Takahashi changed iPS cells made from cells of healthy people into neural precursor cells and transplanted them into the brain of the patient.

[Copyright The Jiji Press, Ltd.]

Jiji Press