Flu Viruses Resistant to New Drug Xofluza Found

Society Lifestyle

Tokyo, Jan. 26 (Jiji Press)--Mutated influenza viruses resistant to baloxavir marboxil, a new anti-flu drug sold as Xofluza, were detected in patients last month, Japan's National Institute of Infectious Diseases has said.

This was the first confirmation of such a virus by a national research institute after the drug was put into practical use in last March, the health ministry said.

According to the NIID, Xofluza-resistant viruses were found in two of four primary school students in Yokohama, Kanagawa Prefecture, in generic screenings in December conducted after they developed flu symptoms earlier the same month.

The mutated viruses were 76-120 times more resistant to the new anti-flu drug, developed by Shionogi & Co. <4507>, than unmutated ones detected in the other two children.

In clinical trials of baloxavir marboxil, resistant viruses were detected in 23.4 pct of participating patients younger than 12 years old.

[Copyright The Jiji Press, Ltd.]

Jiji Press