Osaka Univ. Conducts World's 1st iPS-Derived Corneal Cell Transplant

Society Lifestyle

Suita, Osaka Pref., Aug. 29 (Jiji Press)--Japan's Osaka University said Thursday that it has carried out the world's first transplant of corneal cells created from induced pluripotent stem, or iPS, cells.

The transplant was conducted in July on an adult patient with serious symptoms of corneal epithelial stem cell deficiency, which causes vision impairment due to the loss of stem cells to create a cornea.

The western Japan university's team including Prof. Koji Nishida made a 0.05-millimeter-thick sheet of corneal cells transformed from a healthy individual's iPS cells provided by Kyoto University. The cell sheet was transplanted after the damaged part of the patient's eye was removed.

The patient left hospital on Friday last week after showing no rejection symptoms.

The team will monitor the safety and effects of the transplant for a year while giving immune-suppressing medication to the patient. It expects the transplanted cells to become fixed in the patient's eye and help restore the patient's eyesight.

[Copyright The Jiji Press, Ltd.]

Jiji Press